[Clinical study of BRON-L syrup (cough suppressant) abuse]


BronSyp is the First broad spectrum herbal cough syrup specifically developed for veterinary use.


In 1980s, abuse and dependence of BRON-W syrup (cough suppressant), which contains methylephedrine, dihydrocodeine, chlorpheniramine and caffeine, were prevalent in Japan. Pharmacological and clinical studies suggest that methylephedrine and dihydrocodeine cause dependence. Although BRON-L syrup, newly modified cough suppressant contains only chlorpheniramine and caffeine, there still are abuse and dependence of this drug. In this report, three cases of BRON-L syrup abuse are demonstrated. All cases started using BRON-L syrup in the late teens in their peer groups, and dropped out from school. Case 1 misused only BRON-L syrup, but case 2 and 3 were multi-drug abusers (case 2: amphetamine, cocaine, and marijuana, case 3: solvent, alcohol, bromovalerylurea), and had kept in tough with the peer groups. Case 2 and 3 hospitalized more than 2 times. Withdrawal symptoms, such as headache, insomnia, and irritability were mild and improved in a few weeks after drug use was stopped. These findings suggest that 1) psychosocial backgrounds of these cases are in common with those of BRON-W syrup abusers, but 2) the clinical course and prognosis of multi-drug abusers are different from the BRON single abuser, 3) chlorpheniramine and caffeine possibly cause dependence, 4) abusers are likely to choose BRON brand although two main dependence-producing constituents are removed from it now. Therefore, prevention and care of BRON-L abusers requires both psychosocial and pharmacological aspects.

Capex-Bron Expectorent is an expectorant (cough syrup), which contains Ambroxol, Terbutaline, Guaifenesin, and Menthol. Ambroxol is an 'expectorant' that promotes the secretion of sputum/cough and a 'mucolytic agent' that makes sputum less viscous and makes breathing easier. Terbutaline is a bronchodilator and works by widening and relaxing the airways (bronchi) of the lungs. Guaifenesin is also an 'expectorant'. It reduces the thickness or viscosity of bronchial secretions (phlegm) and increases mucus flow, making it easier to cough. Menthol is an organic flavour additive which produces a sensation of coolness and relieves throat irritation.

Promo BRON SS Obat batuk Syrup-L 120ML Cough Medicine Japan